This book is a project undertaken by EcoHealth Alliance to develop an educational tool usable across many cultural contexts. It aims to provide an informative, thorough, and succinct guide to living at the interface between human settlement and wildlife habitat. In areas where human populations come into high levels of contact with animals, it is essential to ensure responsible practices and behaviors to prevent spillover of zoonotic disease from animal reservoirs to humans. With this book, EcoHealth Alliance hopes to aid people and animals worldwide.

The SARS-CoV-2 virus, the cause of COVID-19, emerged as a human pathogen in 2019. While it is thought to have a zoonotic source, the original wildlife reservoir and any potential intermediate hosts have not yet been identified. Phylogenetic analyses suggest the progenitor virus is related to beta-coronaviruses previously identified in bats. At this time, SARS-CoV-2 should be considered a human pathogen with people acting as reservoir and sustaining transmission. There is a possibility SARS-CoV-2 will become endemic in the human population and thus be considered as a potential reverse zoonosis to wildlife as with infectious diseases such as tuberculosis and influenza.

Currently the risk of human-to-animal transmission to non-captive wildlife species warrants concern. A number of cases have demonstrated natural human-to-animal transmission of SARS-CoV-2 in felids, canids and mustelids, the majority due to close and prolonged contact with infected households or people, and none has involved free-ranging wildlife. The identification of close phylogenetically-related viruses (e.g. in bats and pangolins), the presence of important cell receptor proteins (ACE2 receptors) and infection following natural exposure or experimental inoculation suggest that a wide range of mammalian species may be susceptible to SARS-CoV-2. Knowledge and experience with human-to-animal transmission with other human respiratory pathogens (e.g. metapneumovirus, measles, other human coronaviruses and tuberculosis) indicates that some species taxonomically closely related to humans (e.g. non-human primates) would likely be susceptible to infection and/or clinical disease caused by SARS-CoV-2.

There are valid concerns about the health of individuals or populations if infected with the virus and/or a wildlife population becoming a reservoir for SARS-CoV-2. Any wildlife species/taxa that becomes a reservoir for SARS-CoV-2 could pose a continued public health risk of zoonosis, a risk for the transmission of SARS-CoV-2 to other animal species, and the risk of negative perceptions of that species resulting in human threats to the species or their populations.

Efforts that require working with free-living wildlife are vital to professional management and conservation as well as the health of wildlife, people and ecosystems. The recommendations below were developed to minimize the risk of SARS-CoV-2 transmission from people to freeranging, wild mammals. Specifically, these recommendations are for people engaged in wildlife work* in the field, either in direct contact (e.g. handling) or indirect contact (e.g. within 2 meters or in a confined space) with free-ranging wild mammals, or working in situations in which free[1]ranging wild mammals may come in contact with surfaces or materials contaminated by infected personnel.

This is an introductory course to the IUCN Guidelines for Wildlife Disease Risk Analysis (WDRA). This course is designed to equip participants with an understanding of how to put the guidelines into practice. Our target audiences are government wildlife agency staff, IUCN SSC Specialist Group members, and other conservation professionals and veterinarians working in zoos, aquariums, universities or field programs, responsible for planning for disease management at the interface between people, places and wildlife. By the end of the course, participants will be able to: recognize and justify situations where a WDRA process can contribute to a) wildlife conservation, b) domestic animal health care, and c) public health protection; explain how the principle of One Health and the science of epidemiology are applied to a WDRA; and design a workshop to effectively engage multiple stakeholders in completing a WDRA. Click here to find out more about the course and how to apply to an upcoming session.

The wide-reaching effects of the COVID-19 pandemic have included immense loss of life and serious health and economic consequences across communities and  ecosystems. Tourism, which itself suffered a sharp disruption in the pandemic, is among the industries that have a strong interest to reduce risks and increase resilience toward a more sustainable model in line with a One Health approach. Protected and conserved areas (PCAs) are an especially important setting for sustainable tourism and can serve as a catalyst for wider adoption of best practices anchored in One Health principles that help to sustainability balance the health of people, animals, and  ecosystems. This report presents six core principles, which provide practical strategies for tour operators and wider tourism industry stakeholders in PCAs. They are intentionally broad, allowing for use and adaptation in any PCA context.

Protected and conserved areas (PCAs) are affected by disease risks and impacts in wide-ranging ways, as demonstrated by recent epidemics and the global COVID-19  pandemic. Their potential role in disease prevention, detection, response, and recovery is significant, both to reduce spillover risks and to effectively prepare for disease events. This report provides an orientation for PCA managers on relevant sources of risk, with actions that can be taken to build up systems to manage disease threats across the variety of PCA contexts. A key message is that protected areas can – and should – play a vital role in One Health approaches to reduce disease risk and improve human, animal, and environmental health outcomes.

This IUCN–OIE publication provides a ‘how-to’ guide that will be useful to the growing and diverse range of professionals involved in assessment and management of wildlife-associated disease risk scenarios. The document has been co-written by 22 specialists in the fields of wildlife disease ecology, epidemiology, risk analysis, modelling, disease surveillance, diagnostics, wildlife management, research, teaching and conservation planning. These authors have pooled their knowledge and experience to make tools and processes at the cutting edge of wildlife disease risk analysis accessible to a broad global audience in an effort to ensure healthy ecosystems through better decision making. This is a companion volume to the Guidelines for Wildlife Disease Risk Analysis.