The Mamirauá Institute for Sustainable Development was created in 1999 to provide science, technology and innovation to communities in the Amazon region. This is done with a high level of ethics and responsibility, respecting their traditional knowledge.

The Institute is responsible for the creation of the Mamirauá Reserve. With 1,240,000 hectares, the reserve has the largest wetland area on the planet and is the first Sustainable Development Reserve (IUCN category 6) in Brazil.

In recent decades, Mamiraua has been over-exploited by private companies, so the Institute works closely with local communities to ensure the sustainable use of fisheries resources.