Hainan is a natural gene bank for tropical crop varieties which include many endemic crop varieties such as Shanlan rice, tropical native melons, beans, solanaceous vegetables as well as 15 local breeds of livestock. However, intensive agriculture development, environmental pollution, invasive alien species, urbanization, attrition of traditional production systems, fragmentation, degradation of habitats and climate change put increasing pressure on agrobiodiversity conservation and sustainable use. This Solution presents how conservation and sustainable use of local agricultural genetic diversity in Hainan Province were promoted through the development of incentive mechanisms for farmers to sustain populations of endemic crops and livestock, the establishment of a supportive enabling environment and strengthened institutional capacity.